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Found 2841 with Last Name = 'schepmann' and Initial = 'd'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.0360nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50035105(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50035105(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50361993(CHEMBL1939700)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236864(CHEMBL4096473)
Affinity DataKi:  0.160nMAssay Description:Inhibition of high affinity uptake of [3H]DA using rat nerve endings obtained from brain regions enriched in DAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50259004(1'-[4-Fluorobenzyl]-3H-spiro[[2]benzofuran-1,4'pip...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50396885(CHEMBL2170669)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260587(CHEMBL4062642)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000287(2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-U69593 from KOR in guinea pig brain membranes measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50396850(CHEMBL2170496)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236870(CHEMBL4064380)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252721(1-(Cyclohexylmethyl)-6-methoxy-6,7-dihydrospiro[pi...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]-(+)pentazocine from guinea pig brain sigma 1-type opioid receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252721(1-(Cyclohexylmethyl)-6-methoxy-6,7-dihydrospiro[pi...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50593830(CHEMBL5204491)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes measured after 120 mins by scintillation counting meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236878(CHEMBL4084350)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50316622((S)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((S)...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U-69593 from kappa-opoid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50389025(CHEMBL2064198)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50389025(CHEMBL2064198)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]-(+)pentazocine from guinea pig brain sigma 1-type opioid receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316621((R)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((R)...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50316622((S)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((S)...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50316622((S)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((S)...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252946(1-Benzyl-6-methoxy-6,7-dihydrospiro[piperidine-4,4...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50252946(1-Benzyl-6-methoxy-6,7-dihydrospiro[piperidine-4,4...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-U69593 from KOR in guinea pig brain membranes measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  0.340nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000780(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]U-69593 from kappa-opoid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236871(CHEMBL4069231)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50396883(CHEMBL2170667)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130756(CHEMBL3634515)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50027433(CHEMBL603370 | GR-89696)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50027433(CHEMBL603370 | GR-89696)
Affinity DataKi:  0.360nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260585(CHEMBL4063826)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260591(CHEMBL4084334)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in quinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50325534(CHEMBL267495 | nalfurafine)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321782(1-(cyclohexylmethyl)-1'-phenyl-6',7'-dihydro-1'H-s...)
Affinity DataKi:  0.430nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain sigma 1 receptor after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236886(CHEMBL4099849)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236865(CHEMBL4095192)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346474((R)-4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidi...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50593835(CHEMBL5175714)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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