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Found 402 with Last Name = 'schollmeyer' and Initial = 'd'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27960((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/mole IC50:  3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27959(4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]ami...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/mole IC50:  330nM EC50:  9.10nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27955((-)-Zilpaterol | (9R,10R)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  320nM ΔG°:  -36.7kJ/mole IC50:  620nM EC50:  8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM25769(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Affinity DataKi:  510nM ΔG°:  -35.6kJ/mole IC50:  980nM EC50:  19nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27958(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Affinity DataKi:  570nM ΔG°:  -35.3kJ/mole IC50:  1.30E+3nM EC50:  6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27956((rac)-Zilpaterol | 9-hydroxy-10-(propan-2-ylamino)...)
Affinity DataKi:  580nM ΔG°:  -35.2kJ/mole IC50:  1.10E+3nM EC50:  13nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27957((+)-Zilpaterol | (9S,10S)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  7.00E+3nM ΔG°:  -29.1kJ/mole IC50:  1.70E+4nM EC50:  1.40E+5nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Intervet Innovation

LigandPNGBDBM27955((-)-Zilpaterol | (9R,10R)-9-hydroxy-10-(propan-2-y...)
Affinity DataKi:  1.30E+5nM ΔG°:  -22.0kJ/mole IC50:  3.20E+5nM EC50: >1.00E+6nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343492((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343508(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50:  3nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343507(4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343506((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251985(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392190(CHEMBL2152960)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  6nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392177(CHEMBL2152946)
Affinity DataIC50:  8nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392172(CHEMBL2152941)
Affinity DataIC50:  8nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392169(CHEMBL2152938)
Affinity DataIC50:  8nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392181(CHEMBL2152950)
Affinity DataIC50:  8nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50398458(CHEMBL2179117)
Affinity DataIC50:  8nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50:  9nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392178(CHEMBL2152947)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392180(CHEMBL2152949)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392179(CHEMBL2152948)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343502((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343504((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50398457(CHEMBL2179118)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343493((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343487((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343489(CHEMBL1773502 | N-Cyclohexyl-4-(4-(4-fluorophenyl)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50398464(CHEMBL2179115)
Affinity DataIC50:  15nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50398466(CHEMBL2179128)
Affinity DataIC50:  16nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  17nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343488(CHEMBL1773421 | rac-N-Cyclohexyl-4-(4-(4-fluorophe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343486(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  19nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392161(CHEMBL2152793)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392191(CHEMBL2152961)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392167(CHEMBL2152936)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392185(CHEMBL2152955)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392187(CHEMBL2152957)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392198(CHEMBL2152969)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50392148(CHEMBL2152778)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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