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Found 8 with Last Name = 'schwarcz' and Initial = 'r'
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat brain KAT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of KAT2 in human prefrontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target3-hydroxyanthranilate 3,4-dioxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50446510(CHEMBL3110069)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of 3-HAO in human brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50416560(CHEMBL1215660)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyanthranilate 3,4-dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50446510(CHEMBL3110069)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 3-HAO in Sprague-Dawley rat brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant MBP-KAT1 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
University Of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of KAT1 in human prefrontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed