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Found 435 with Last Name = 'scullion' and Initial = 'p'
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313480(4-(cyclohexylamino)-6-(piperazin-1-yl)-1,3,5-triaz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323257(1-methyl-6-(4-(pyridin-2-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50467024(CHEMBL4280697)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50364113(CHEMBL1230468)
Affinity DataIC50:  3nMAssay Description:Inhibition of human N-myristoyltransferase 2 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50364113(CHEMBL1230468)
Affinity DataIC50:  3nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323087(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9H-purine-6...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323087(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9H-purine-6...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033418(CHEMBL3357685)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313477(4-(3-(pentan-3-ylamino)propyl)-6-(3-(trifluorometh...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313476(4-(3-(piperidin-1-yl)propyl)-6-(3-(trifluoromethyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033616(CHEMBL3358119)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033485(CHEMBL3357702)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033480(CHEMBL3357697)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323088(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9-(2-hydrox...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033618(CHEMBL3358121)
Affinity DataIC50:  5nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033617(CHEMBL3358120)
Affinity DataIC50:  5nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033482(CHEMBL3357699)
Affinity DataIC50:  5nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322917(4-(4-ethoxy-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in mouse splenocytes assessed as accumulation of lip10 by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323089(9-(3-(dimethylamino)propyl)-2-(4-ethoxy-3-(trifluo...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323092(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9-ethyl-9H-...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323248(1-methyl-6-(4-(2-(3-oxopiperazin-1-yl)ethoxy)-3-(t...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323253(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033478(CHEMBL3357695)
Affinity DataIC50:  8nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033619(CHEMBL3358122)
Affinity DataIC50:  8nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033414(CHEMBL3357681)
Affinity DataIC50:  9nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033487(CHEMBL3357704)
Affinity DataIC50:  9nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033614(CHEMBL3358117)
Affinity DataIC50:  9nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323245(1-methyl-6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313478(4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323255(1-methyl-6-(4-(pyridin-4-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323085(4-(4-methyl-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313474(4-cyclooctyl-6-propylpyrimidine-2-carbonitrile | C...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313467(4-(3-tert-butylphenyl)-6-propylpyrimidine-2-carbon...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313467(4-(3-tert-butylphenyl)-6-propylpyrimidine-2-carbon...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033415(CHEMBL3357682)
Affinity DataIC50:  12nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
Affinity DataIC50:  12nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323084(4-(4-fluoro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50316768((Z,Z)-5-[3-Chloro-4-((2S)-2,3-dihydroxy-propoxy)-b...)
Affinity DataIC50:  13nMAssay Description:Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323256(1-methyl-6-(4-(pyridin-3-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323251(1-methyl-6-(4-(piperidin-4-ylmethoxy)-3-(trifluoro...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323086(4-(4-methoxy-3-(trifluoromethyl)phenyl)-6-propylpy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50323085(4-(4-methyl-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50033488(CHEMBL3357705)
Affinity DataIC50:  17nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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