Found 6018 with Last Name = 'shu' and Initial = 'k' 
Affinity DataKi: 0.0100nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.0400nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [G157C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 0.190nM ΔG°: -55.5kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T206C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 0.830nM ΔG°: -51.8kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V202C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 1.5nM ΔG°: -50.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T206C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 2.10nM ΔG°: -49.5kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T162C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 2.20nM ΔG°: -49.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [G200C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3nM ΔG°: -48.6kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.10nM ΔG°: -48.1kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,D95C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.10nM ΔG°: -48.6kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R224C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.30nM ΔG°: -48.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.30nM ΔG°: -47.9kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R183C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.70nM ΔG°: -48.1kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Agonistic activity of the compound towards retinoid X receptor-betaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,L179C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.80nM ΔG°: -48.1kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [A160C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 4nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R233C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 4.10nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V211C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 4.10nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-betaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T120C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 4.40nM ΔG°: -47.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T165C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 4.40nM ΔG°: -47.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 5.10nM ΔG°: -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 5.70nM ΔG°: -46.6kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Selective activity of the compound towards retinoid X receptor-betaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S205C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 6.5nM ΔG°: -46.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 8.10nM ΔG°: -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Selective activity of the compound towards retinoid X receptor-gammaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S204C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 8.80nM ΔG°: -46.0kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T181C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 9.20nM ΔG°: -45.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,A118C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 9.20nM ΔG°: -45.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-200],P14867[176-456](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 9.60nM ΔG°: -45.8kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Agonistic activity of the compound towards retinoid X receptor-gammaMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Agonistic activity of the compound towards retinoid X receptor-alphaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R171C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 13nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,M169C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 13.8nM ΔG°: -44.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [F99C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 15nM ΔG°: -44.2kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,M169C](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 15.5nM ΔG°: -44.6kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Selective activity of the compound towards retinoid X receptor-alphaMore data for this Ligand-Target Pair
