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Found 134 with Last Name = 'sidique' and Initial = 's'
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253982(CHEMBL461194 | N-(2-hydroxyethyl)-3-(2,3,4-trichlo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254415(3-(2,4-dichlorophenyl)-N-(3-hydroxypropyl)-1H-pyra...)
Affinity DataIC50:  31nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254026(3-(2,4-difluorophenyl)-N-(2-hydroxyethyl)-1H-pyraz...)
Affinity DataIC50:  35nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254416(3-(2,4-dichlorophenyl)-N-(4-hydroxybutyl)-1H-pyraz...)
Affinity DataIC50:  35nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254414(3-(2,4-dichlorophenyl)-1H-pyrazole-5-carbohydrazid...)
Affinity DataIC50:  44nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254319(3-(2,4-dichlorophenyl)-N-(2-hydroxyethyl)-1H-pyraz...)
Affinity DataIC50:  44nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254417(3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-1H-pyraz...)
Affinity DataIC50:  46nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253955(3-(2,4-dichlorophenyl)-N,N-bis(2-hydroxyethyl)-1H-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254320(3-(2,4-dichlorophenyl)-N-isopropyl-1H-pyrazole-5-c...)
Affinity DataIC50:  51nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253959(3-(2,4-dichloro-5-fluorophenyl)-N-(3-hydroxypropyl...)
Affinity DataIC50:  56nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253956(3-(2,4-dichlorophenyl)-N-isobutyl-1H-pyrazole-5-ca...)
Affinity DataIC50:  82nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254411(3-(2,4-dichloro-5-fluorophenyl)-N-(2-hydroxyethyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM35491(Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)...)
Affinity DataIC50:  105nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  110nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254321(3-(2,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-5-...)
Affinity DataIC50:  119nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253960(3-(2,4-dichloro-5-fluorophenyl)-N,N-bis(2-hydroxye...)
Affinity DataIC50:  127nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254025(CHEMBL461425 | N-(2-hydroxyethyl)-3-(2,4,5-trifluo...)
Affinity DataIC50:  134nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253958(3-(2,4-dichlorophenyl)-N,N-diethyl-1H-pyrazole-5-c...)
Affinity DataIC50:  285nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302021(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  310nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254412(3-(2,4-dichloro-5-fluorophenyl)-N,N-dimethyl-1H-py...)
Affinity DataIC50:  324nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254372((3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(4-(2-hydr...)
Affinity DataIC50:  375nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254369(CHEMBL509575 | N-tert-butyl-3-(2,4-dichlorophenyl)...)
Affinity DataIC50:  398nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50253957(3-(2,4-dichlorophenyl)-N-isopentyl-1H-pyrazole-5-c...)
Affinity DataIC50:  459nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254371((3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(4-ethylpi...)
Affinity DataIC50:  488nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254318((2,4-dihydrochromeno[4,3-c]pyrazol-3-yl)(pyrrolidi...)
Affinity DataIC50:  500nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254316(CHEMBL467705 | cid_6472157 | methyl 3-(2,4-dichlor...)
Affinity DataIC50:  500nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254373((3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(morpholin...)
Affinity DataIC50:  574nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254370((3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(4-methylp...)
Affinity DataIC50:  828nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302022(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  970nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254315(3-(2-chlorophenyl)-1H-pyrazole-5-carboxylic acid |...)
Affinity DataIC50:  980nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302023(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254317(2,4-dihydrochromeno[4,3-c]pyrazole-3-carboxylic ac...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM32778(MLS000081703 | SMR000062919 | [2-(2-cyanoethyl)-5-...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254374(CHEMBL468686 | azepan-1-yl(3-(2,4-dichlorophenyl)-...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302024(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302025(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302026(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335242(3-Chloro-3'-((2-cyclopentyl-3-oxo-2,3-dihydrobenzo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302011(1-(4-methoxybenzyl)-3-methyl-1H-pyrazol-5-yl benzo...)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302027(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  4.28E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50254413(3-(2,4-dichloro-5-fluorophenyl)-N-isopropyl-1H-pyr...)
Affinity DataIC50:  4.85E+3nMAssay Description:Inhibition of TNSALP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302002(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302003(5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-y...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335242(3-Chloro-3'-((2-cyclopentyl-3-oxo-2,3-dihydrobenzo...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50302012(1-benzyl-3-methyl-1H-pyrazol-5-yl 2,6-difluorobenz...)
Affinity DataIC50:  8.04E+3nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335253(4-Chloro-3'-((2-cyclopentyl-1-oxoisoindolin-5-ylox...)
Affinity DataIC50:  8.15E+3nMAssay Description:Inhibition of radioligand binding to human adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335253(4-Chloro-3'-((2-cyclopentyl-1-oxoisoindolin-5-ylox...)
Affinity DataIC50:  8.15E+3nMAssay Description:Inhibition of radioligand binding to human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335253(4-Chloro-3'-((2-cyclopentyl-1-oxoisoindolin-5-ylox...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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