TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent estrogen ES2 from human recombinant ERbeta by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of fluorescent estrogen ES2 from human recombinant ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibitory constant against Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 34.1nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 41.5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]estradiol from estrogen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]estradiol from estrogen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair