Affinity DataKi: 0.0800nM ΔG°: -57.1kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nM ΔG°: -56.3kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -51.0kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
Affinity DataKi: 450nM ΔG°: -35.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 540nM ΔG°: -35.3kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nM ΔG°: -32.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+3nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:Inhibitory activity against rat ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 7.60E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 8.80E+4nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+4nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.21E+5nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase activity was measured by the maleate dehydrogenase catalyzed reduction of oxaloacetat...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.31E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+5nMAssay Description:Inhibition of recombinant ATP-Citrate Lyase activity as maleate dehydrogenase catalyzed reduction of oxaloacetate by NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.75E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair
Affinity DataKi: 1.78E+5nMAssay Description:Inhibitory activity against rat ATP-citrate lyase activity by the maleate dehydrogenase catalyzed reduction of oxaloacetate by NADH.More data for this Ligand-Target Pair