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Found 221 with Last Name = 'tan' and Initial = 'sl'
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  300nM ΔG°:  -34.7kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  520nM ΔG°:  -33.5kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  1.20E+3nM ΔG°:  -31.5kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92914(Aryl 1-indanylketone, 3)
Affinity DataKi:  1.70E+3nM ΔG°:  -30.7kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92915(Aryl 1-indanylketone, 4)
Affinity DataKi:  2.10E+3nM ΔG°:  -30.2kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  2.42E+3nM ΔG°:  -29.9kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  6.28E+3nM ΔG°:  -27.7kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92914(Aryl 1-indanylketone, 3)
Affinity DataKi:  8.60E+3nM ΔG°:  -27.0kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92916(Aryl 1-indanylketone, 5)
Affinity DataKi:  1.00E+4nM ΔG°:  -26.6kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  1.20E+4nM ΔG°:  -26.2kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92918(Benzofuranone, 7)
Affinity DataKi:  2.10E+4nM ΔG°:  -24.9kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase-like 1(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  2.90E+4nM ΔG°:  -24.2kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92920(Benzofuranone, 9)
Affinity DataKi:  6.30E+4nM ΔG°:  -22.4kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92916(Aryl 1-indanylketone, 5)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92917(Aryl 1-indanylketone, 6)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92918(Benzofuranone, 7)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92919(Benzofuranone, 8)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase C(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92919(Benzofuranone, 8)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase H(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase C(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase-like 1(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92917(Aryl 1-indanylketone, 6)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92920(Benzofuranone, 9)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase H(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.3kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426607(CHEMBL2325897)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426606(CHEMBL2325903)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426604(CHEMBL2325906)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426616(CHEMBL2325899)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426602(CHEMBL2325894)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426615(CHEMBL2325900)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426603(CHEMBL2325912)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50498583(CHEMBL3609639)
Affinity DataIC50:  10nMAssay Description:Inhibition of gamma-secretase in human SH-SY5Y cells expressing beta-APP C-terminal fragment SPA4CT assessed as decrease of amyloid beta-42 level by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426606(CHEMBL2325903)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426604(CHEMBL2325906)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426605(CHEMBL2325904)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426614(CHEMBL2325905)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426615(CHEMBL2325900)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426603(CHEMBL2325912)
Affinity DataIC50:  23nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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