Affinity DataKi: 1.70nMAssay Description:Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Non-competitive inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Affinity DataKi: 7.60E+3nMAssay Description:Mixed-type inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant IDE exosite (unknown origin) expressed in Escherichia coli using insulin as substrate incubated for 4 hrs by AlphaLisa assa...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type human IDE catalytic site using insulin as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human telomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of IDE exosite and catalytic site (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to Adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair