Affinity DataKi: 1nMAssay Description:Reversible inhibition of STS (unknown origin) using 4-MUS as substrate measured over 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Reversible inhibition of STS (unknown origin) using 4-MUS as substrate measured over 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of steroid sulfatase using 4-methylumbelliferyl sulfate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 5 mins by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed type inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Mixed type inhibition of steroid sulfatase using 4-methylumbelliferyl sulfate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 112nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 128nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 153nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 156nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 195nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 208nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of cloned human transmembrane, tumor-associated isozyme CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 273nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 348nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 357nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 415nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair
Affinity DataKi: 565nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 645nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IIMore data for this Ligand-Target Pair
Affinity DataKi: 714nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
Affinity DataKi: 785nMAssay Description:Inhibition of recombinant human mitochondrial isozyme CA VAMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Binding affinity towards the binding site in PTP1B enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 952nMAssay Description:Inhibition of recombinant human cytosolic isozyme CA IMore data for this Ligand-Target Pair