Affinity DataKi: 0.330nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human cloned dopamine receptor D2S expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity towards human Dopamine receptor D2 (short) by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals
Curated by ChEMBL
Guilford Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibitory activity against FK506 binding protein 12More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair