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Found 76 with Last Name = 'thompson' and Initial = 'rc'
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135773(2-(4-{3-[1-(3,4-Dimethyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135777(2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135775(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4-prop...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135782(2-(4-{3-[1-(3-Methoxy-benzyl)-5-oxo-4-propyl-4,5-d...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135780(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4,5-di...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135779(2-(4-{3-[4-(2-Hydroxy-ethyl)-1-(4-methyl-benzyl)-5...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135781(2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135774(2-{4-[3-(1-Cyclohexylmethyl-5-oxo-4-propyl-4,5-dih...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490735(CHEMBL1863002 | DNDI1449875)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135777(2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  520nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490750(CHEMBL2334336)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135773(2-(4-{3-[1-(3,4-Dimethyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  740nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490748(CHEMBL1863056 | DNDI1435775)
Affinity DataIC50:  810nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135774(2-{4-[3-(1-Cyclohexylmethyl-5-oxo-4-propyl-4,5-dih...)
Affinity DataIC50:  880nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135776(2-(4-{3-[4-Carboxymethyl-1-(4-methyl-benzyl)-5-oxo...)
Affinity DataIC50:  960nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490744(CHEMBL1862905 | DNDI1467768)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490737(CHEMBL1863288 | DNDI1538112)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135775(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4-prop...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490736(CHEMBL1863145 | DNDI1343536)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135781(2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135777(2-(4-{3-[1-(4-tert-Butyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135773(2-(4-{3-[1-(3,4-Dimethyl-benzyl)-4-methyl-5-oxo-4,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135774(2-{4-[3-(1-Cyclohexylmethyl-5-oxo-4-propyl-4,5-dih...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490742(CHEMBL1863462 | DNDI1460901)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490749(CHEMBL1862798 | DNDI1434923)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490743(CHEMBL1863046 | DNDI1434940)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135782(2-(4-{3-[1-(3-Methoxy-benzyl)-5-oxo-4-propyl-4,5-d...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490753(CHEMBL1863455 | DNDI1465083)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490741(CHEMBL2334337)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490751(CHEMBL1863306 | DNDI1434944)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490745(CHEMBL1863273 | DNDI1338491)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135780(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4,5-di...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490746(CHEMBL1863393 | DNDI1388149)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490752(CHEMBL1862941 | DNDI1551253)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135779(2-(4-{3-[4-(2-Hydroxy-ethyl)-1-(4-methyl-benzyl)-5...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135775(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4-prop...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490738(CHEMBL1863131 | DNDI1490391)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135781(2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135779(2-(4-{3-[4-(2-Hydroxy-ethyl)-1-(4-methyl-benzyl)-5...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135782(2-(4-{3-[1-(3-Methoxy-benzyl)-5-oxo-4-propyl-4,5-d...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135780(2-Methyl-2-(4-{3-[1-(4-methyl-benzyl)-5-oxo-4,5-di...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490747(CHEMBL1863090 | DNDI1449876)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490740(CHEMBL1862938 | DNDI1467767)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490739(CHEMBL1862975 | DNDI1335908)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135776(2-(4-{3-[4-Carboxymethyl-1-(4-methyl-benzyl)-5-oxo...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50266776(CHEMBL4066553)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsome using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50556552(CHEMBL583256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsome using testosterone as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
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