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Found 64 with Last Name = 'townsend' and Initial = 'jt'
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168854(4-(1-Ethyl-7-piperazin-1-ylmethyl-1H-imidazo[4,5-c...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168577(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168577(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168858((R,S)-4-(1-Piperidin-3-yl-1H-imidazo[4,5-c]pyridin...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168856(4-[1-(3-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyrid...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168587(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168869(1-[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168587(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168862(4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyrid...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168861(4-(4-Chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168581(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168853(4-(1-Ethyl-7-piperidin-1-ylmethyl-1H-imidazo[4,5-c...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168866(4-(1-Ethyl-4-methyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168867(4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168864((R,S)-4-[1-(2-Amino-1-methyl-ethyl)-1H-imidazo[4,5...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168581(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168578(4-[1-(1-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168868(4-[1-(4-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168594(2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidazol-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168601(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168601(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168576(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyrazin-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168859(4-[1-(3-Amino-propyl)-1H-imidazo[4,5-c]pyridin-2-y...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168595(4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168586(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against selected kinase p70S6KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168589(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)
Affinity DataIC50:  107nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against selected kinase DYRK1-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168582(4-(1-Methyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Affinity DataIC50:  126nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168588(4-(1-Ethyl-1H-benzoimidazol-2-yl)-furazan-3-ylamin...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50:  169nMAssay Description:Inhibitory concentration against selected kinase CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168863(4-(4-Ethoxy-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  174nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168855(4-(1-Ethyl-4-methoxy-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50:  209nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168865(4-(1,4-Diethyl-1H-imidazo[4,5-c]pyridin-2-yl)-fura...)
Affinity DataIC50:  229nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168593(2-(4-Amino-furazan-3-yl)-3-ethyl-3H-benzoimidazol-...)
Affinity DataIC50:  258nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against selected kinase p70S6KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168852(4-[1-(3-Dimethylamino-propyl)-1H-imidazo[4,5-c]pyr...)
Affinity DataIC50:  617nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168857(4-(1-Ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50:  813nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168598(CHEMBL185731 | [2-(4-Amino-furazan-3-yl)-1-ethyl-1...)
Affinity DataIC50:  974nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168592(4-(1-Ethyl-5-methoxy-1H-benzoimidazol-2-yl)-furaza...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168599(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,5-dime...)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168584(4-(3-Ethyl-3H-imidazo[4,5-c]pyridin-2-yl)-furazan-...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168600(4-(1H-Imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamin...)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168591(4-(1-Ethyl-6-fluoro-1H-benzoimidazol-2-yl)-furazan...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50168870(4-(1-Ethyl-4-pyrrolidin-1-yl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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