Affinity DataKi: 0.0120nMAssay Description:Displacement of [125I]Iodocyanopindolol from human adrenergic beta2 receptor expressed in insect sf9 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0230nMAssay Description:Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Canterbury
Curated by PDSP Ki Database
University of Canterbury
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Affinity DataKi: 0.600nMAssay Description:Binding affinity of compound towards Dopamine receptor D2 using [3H]raclopride (1.2 nM) ligand in striatum bovine was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity of compound towards Alpha-1 adrenergic receptor using [3H]prazosin 0.5 nM ligand in frontal cortex calf was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 1.58nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Canterbury
Curated by PDSP Ki Database
University of Canterbury
Curated by PDSP Ki Database
Affinity DataKi: 1.90nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
Affinity DataKi: 2.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 2.51nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 2.51nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Reading
Curated by PDSP Ki Database
University of Reading
Curated by PDSP Ki Database
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Canterbury
Curated by PDSP Ki Database
University of Canterbury
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1C receptor using [3H]mesulergine (1.2 nM) ligand in choroid Plexus pig was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Canterbury
Curated by PDSP Ki Database
University of Canterbury
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Canterbury
Curated by PDSP Ki Database
University of Canterbury
Curated by PDSP Ki Database
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair