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Found 17 with Last Name = 'tsai' and Initial = 'sc'
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359989(CHEMBL1927943)
Affinity DataIC50:  300nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105987(CHEMBL125441 | [5-(1-Benzyl-6-methoxy-1H-indazol-3...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105986(1-Benzyl-6-fluoro-3-(5-methoxymethyl-furan-2-yl)-1...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105994(CHEMBL440716 | [5-(1-Benzyl-6-methyl-1H-indazol-3-...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50106010(1-Benzyl-3-(5-methoxymethyl-furan-2-yl)-6-methyl-1...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359990(PRUNETIN)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105983(1-Benzyl-3-(5-methoxymethyl-furan-2-yl)-1H-indazol...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105999(CHEMBL123034 | [5-(1-Benzyl-6-fluoro-1H-indazol-3-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359988(CHEMBL1927942)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50312648((2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-d...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105989(1-Benzyl-3-(5-methyl-furan-2-yl)-1H-indazole | CHE...)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50207159(2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50095469((5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol |...)
Affinity DataIC50:  3.19E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50106006(CHEMBL340558 | [5-(1-Phenyl-1H-indazol-3-yl)-furan...)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50105996(CHEMBL121831 | [5-(1-Benzyl-1H-indazol-3-yl)-furan...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Institute Of Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM15336(1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of PDE5 from plateletsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50225106((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed