Compile Data Set for Download or QSAR
maximum 50k data
Found 866 with Last Name = 'tulshian' and Initial = 'db'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202775(8-(furan-2-yl)-3-(2-(4-(4-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202777(3-(2-(4-(4-chloro-2-fluorophenyl)piperazin-1-yl)et...)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204794(8-(8-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26927(3-[2-(butylamino)ethyl]-8-[(2,6-dichlorophenyl)met...)
Affinity DataKi:  0.400nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26946(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  0.400nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202771(8-(furan-2-yl)-3-(2-(4-(4-(2-methoxyethoxy)-2-(tri...)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202788(3-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-8-(f...)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26945(3-[2-(butylamino)ethyl]-8-(4,4-dimethyl-1,2,3,4-te...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26924(3-[2-(cyclobutylamino)ethyl]-8-[(2,6-dichloropheny...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26923(3-{2-[(cyclopropylmethyl)amino]ethyl}-8-[(2,6-dich...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26926(8-[(2,6-dichlorophenyl)methyl]-3-{2-[(2-methylprop...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26942(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26954(3-[2-(butylamino)ethyl]-8-(6-chloro-4,4-dimethyl-1...)
Affinity DataKi:  0.600nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26925(8-[(2,6-dichlorophenyl)methyl]-1-phenyl-3-[2-(prop...)
Affinity DataKi:  0.600nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26950(3-{2-[(cyclohexylmethyl)amino]ethyl}-8-(4,4-dimeth...)
Affinity DataKi:  0.700nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26922(8-[(2,6-dichlorophenyl)methyl]-1-phenyl-3-[2-(prop...)
Affinity DataKi:  0.700nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26921(8-[(2,6-dichlorophenyl)methyl]-3-[2-(ethylamino)et...)
Affinity DataKi:  0.700nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202790(8-(furan-2-yl)-3-(2-(4-(4-(2-methoxyethoxy)phenyl)...)
Affinity DataKi:  0.700nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202779(3-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  0.700nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26941(3-{2-[(cyclopropylmethyl)amino]ethyl}-8-(4,4-dimet...)
Affinity DataKi:  0.800nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202769(3-(2-(4-(2-fluoro-4-(2-methoxyethoxy)phenyl)pipera...)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26920(8-[(2,6-dichlorophenyl)methyl]-3-[2-(methylamino)e...)
Affinity DataKi:  0.800nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204769(8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204768(8-(7-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202766(3-(2-(4-(4-fluorophenyl)piperidin-1-yl)ethyl)-8-(f...)
Affinity DataKi:  0.900nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26936(3-[2-(cyclopentylamino)ethyl]-8-(4,4-dimethyl-1,2,...)
Affinity DataKi:  0.900nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26937(3-[2-(cyclohexylamino)ethyl]-8-(4,4-dimethyl-1,2,3...)
Affinity DataKi:  0.900nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202773(8-(furan-2-yl)-3-(2-(4-(4-(2-methoxyethoxy)phenyl)...)
Affinity DataKi:  0.900nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26939(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  0.900nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202783(3-(2-(4-(5-chloropyridin-2-yl)piperazin-1-yl)ethyl...)
Affinity DataKi:  0.900nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26938(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26928(8-[(2,6-dichlorophenyl)methyl]-3-[2-(diethylamino)...)
Affinity DataKi:  1nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202767(8-(furan-2-yl)-3-(2-(4-(5-methylpyridin-2-yl)piper...)
Affinity DataKi:  1nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50169328(5-{4-[3-(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.10nMAssay Description:In vitro ability to displace [3H]-SCH-58,261 from A2A adenosine receptor in RatMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204783(1-phenyl-8-(1-phenyl-pentyl)-1,3,8-triaza-spiro[4....)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50087008(8-indan-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26947(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26947(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.30nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165053(6-Furan-2-yl-9-naphthalen-2-ylmethyl-9H-purin-2-yl...)
Affinity DataKi:  1.40nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50087015(1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50169314(2-Furan-2-yl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-c]...)
Affinity DataKi:  1.40nMAssay Description:In vitro ability to displace [3H]-SCH-58,261 from A2A adenosine receptor in RatMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26944(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.40nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26935(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.40nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204764(8-(6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202789(3-(2-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)eth...)
Affinity DataKi:  1.40nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26940(3-[2-(cyclobutylamino)ethyl]-8-(4,4-dimethyl-1,2,3...)
Affinity DataKi:  1.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202772(3-benzyl-8-(furan-2-yl)-3H-[1,2,4]triazolo[1,5-g]p...)
Affinity DataKi:  1.5nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204785(8-(4-methyl-1-phenyl-pentyl)-1-phenyl-1,3,8-triaza...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26934(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.60nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202782(8-(furan-2-yl)-3-(2-(4-(thiazol-2-yl)piperazin-1-y...)
Affinity DataKi:  1.70nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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