Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.165nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.193nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.197nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.256nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.267nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.278nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.332nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.522nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.564nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
Affinity DataKi: 408nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: 3.70E+4nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of SCD1 in HEK293A cell microsomes assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of SCD1 in mouse microsome assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of SCD1 in mouse microsome assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 minsMore data for this Ligand-Target Pair