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Found 223 with Last Name = 'vales' and Initial = 'k'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523376(CHEMBL4589980)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50028685(CHEMBL3356536)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523394(CHEMBL4448188)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50099602(CHEMBL3343931)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523387(CHEMBL4556281)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523391(CHEMBL4449083)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523377(CHEMBL4559593)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523376(CHEMBL4589980)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523387(CHEMBL4556281)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523377(CHEMBL4559593)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523375(CHEMBL4555818)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523389(CHEMBL4559477)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50279984(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523383(CHEMBL4438120)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523393(CHEMBL4466307)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523375(CHEMBL4555818)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523379(CHEMBL4467355)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50265253((S)-2-amino-3-(1H-indol-3-yl)-N-(2-(1,2,3,4-tetrah...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523373(CHEMBL4552440)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50279984(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523371(CHEMBL4456435)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523386(CHEMBL4541558)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8985(6-methyl-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523382(CHEMBL4563209)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523382(CHEMBL4563209)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523371(CHEMBL4456435)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523380(CHEMBL4586157)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569761(CHEMBL4845734)
Affinity DataIC50:  104nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569763(CHEMBL4856125)
Affinity DataIC50:  107nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50099602(CHEMBL3343931)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523389(CHEMBL4559477)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523373(CHEMBL4552440)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523384(CHEMBL4459416)
Affinity DataIC50:  123nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50279983(8-Methyl-1,2,3,4-tetrahydro-acridin-9-ylamine | CH...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523392(CHEMBL4582203)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523393(CHEMBL4466307)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523386(CHEMBL4541558)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523391(CHEMBL4449083)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523381(CHEMBL4444822)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523394(CHEMBL4448188)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523374(CHEMBL4472570)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569763(CHEMBL4856125)
Affinity DataIC50:  255nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM10487(1-chloro-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-...)
Affinity DataIC50:  311nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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