Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:Percent inhibition against 11-beta-hydroxysteroid dehydrogenase 2 of wistar rat kidney at 10 microM was determined using [3H]-cortisolMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against 17 beta hydroxysteroid dehydrogenase type 1 in T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of 17beta-HSD1 expressed in intact human T47D cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Compound was tested for inhibition of human carbonic anhydrase (hCA II)More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against 17 beta hydroxysteroid dehydrogenase type 1 in T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair