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Found 830 with Last Name = 'viklund' and Initial = 'j'
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255582(CHEMBL4078783)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255603(CHEMBL4083992)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255566(CHEMBL4094252)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255598(CHEMBL4064004)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255568(CHEMBL4091768)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255621(CHEMBL4070624)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255622(CHEMBL4067896)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255624(CHEMBL4101983)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255581(CHEMBL4073623)
Affinity DataIC50: <0.100nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as concentration required to achieve half of the maximal stabilization of protein at 54 degC af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255583(CHEMBL4096813)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM528011(US11179399, Example 44_1)
Affinity DataIC50:  1nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255623(CHEMBL4072758)
Affinity DataIC50:  1nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172920(3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(pip...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50211306(4-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(2-(...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory concentration against c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255585(CHEMBL4094381)
Affinity DataIC50:  2nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM527982(US11179399, Example 25_1)
Affinity DataIC50:  2nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM528009(US11179399, Example 43_1)
Affinity DataIC50:  3nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM528013(6-[4-acetyl-2-(trifluoromethyl)piperazin-1-yl]-4-[...)
Affinity DataIC50:  3nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172919(3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-benza...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory concentration against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172919(3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-benza...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory concentration against c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172921(3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-N-(3-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory concentration against c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172921(3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-N-(3-...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory concentration against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM527981((R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-[2-(...)
Affinity DataIC50:  4nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM527937(6-[2-(3-methoxyphenyl)pyrrolidin-1-yl]-4-(3-methyl...)
Affinity DataIC50:  4nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50172920(3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(pip...)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory concentration against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532962(N-[4-[2-[4-ethylsulfonyl-2-(trifluoromethyl)pipera...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532963(N-[4-[2-(3-cyclopropylmorpholin-4-yl)-6-oxo-1H-pyr...)
Affinity DataIC50:  5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532964(N-[4-[2-oxo-6-[2-(trifluoromethyl)phenyl]-1H-pyrid...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532965(N-[4-[2-oxo-6-[2-(trifluoromethyl)-3-pyridyl]-1H-p...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255584(CHEMBL4089106)
Affinity DataIC50:  5nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255615(CHEMBL4061204)
Affinity DataIC50:  5nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532262(4-(2-anilinopyrimidin-4-yl)-6-(2-chlorophenyl)-1H-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532263(4-(2-Anilinopyrimidin-4-yl)-6-(3-pyridyl)-1H-pyrid...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532265(4-(2-anilinopyrimidin-4-yl)-6-morpholino-1H-pyridi...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532266(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532267(4-(2-Anilinopyrimidin-4-yl)-6-[2-(trifluoromethyl)...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532268(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532269(4-(2-Anilinopyrimidin-4-yl)-6-[3-(trifluoromethyl)...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532270(6-[4-[(4-Fluorophenyl)methylsulfonyl]-2-(trifluoro...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532271(6-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532272(4-[2-(Oxazol-2-ylamino)-4-pyridyl]-6-[3-(trifluoro...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532274(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532277(6-(4-Methyl-3-pyridyl)-4-[2-[(2-methylpyrimidin-4-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532278(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532279(6-[1-Ethyl-3-(trifluoromethyl)pyrazol-4-yl]-4-[2-[...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532281(6-(2-Chlorophenyl)-4-[2-[(2-methylpyrimidin-4-yl)a...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience

US Patent
LigandPNGBDBM532262(4-(2-anilinopyrimidin-4-yl)-6-(2-chlorophenyl)-1H-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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