Found 60 with Last Name = 'weigelt' and Initial = 'j' 
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
3D Structure (crystal)TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of full length ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of full length ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of catalytic domain of ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of full length ATRD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length ATRD3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Experiments todetermine IC50 values were conducted with compound concentrationsin the range between 10 nM and 450 μM with a DMSO concentrationof...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
Affinity DataKd: >2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 1.12E+4nMAssay Description:Binding affinity at human recombinant ARTD8 expressed in Escherichia coli BL21 (DE3) R3 pRARE cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
