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maximum 50k data
Found 147 with Last Name = 'wilkinson' and Initial = 'se'
TargetProtein kinase C alpha type(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...)
Affinity DataIC50:  2.85nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C gamma type(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of Protein kinase C gamma (PKC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Protein kinase C betaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
Affinity DataIC50:  19nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3178(3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...)
Affinity DataIC50:  26nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3176(Bisindolylmaleimide 11c | [(4-{3-[4-(1-methyl-1H-i...)
Affinity DataIC50:  28nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50:  30.5nMAssay Description:Inhibition of Protein kinase C betaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3180(3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-ind...)
Affinity DataIC50:  31nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3171(3-(1-methyl-1H-indol-3-yl)-4-{1-[3-(methylamino)pr...)
Affinity DataIC50:  35nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50:  36.5nMAssay Description:Inhibition of Protein kinase C gamma (PKC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3174(Bisindolylmaleimide 11a | ROCHE screening, 56 | [(...)
Affinity DataIC50:  41nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  45nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3177(Bisindolylmaleimide 11d | ROCHE screening, 58 | [(...)
Affinity DataIC50:  47nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282632(3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50:  55nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50:  64nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
Affinity DataIC50:  75nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
Affinity DataIC50:  76nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3173(Bisindolylmaleimide 9 | Trimethyl[3-[3-[3-(1-methy...)
Affinity DataIC50:  93nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50:  105nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2606(3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H...)
Affinity DataIC50:  110nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50:  170nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2607(3-(1,5-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50:  170nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
Affinity DataIC50:  280nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2626(3-(1,7-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50:  280nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
Affinity DataIC50:  300nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2620(3-(6-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50:  310nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2594((Arylindolyl)maleimide deriv. 16 | 3-(1-methyl-1H-...)
Affinity DataIC50:  360nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2612(3-(1-methyl-1H-indol-3-yl)-4-[1-methyl-5-(methylsu...)
Affinity DataIC50:  380nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2635(3-(1-methyl-1H-indol-3-yl)-4-[1-methyl-2-(methylsu...)
Affinity DataIC50:  440nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2634(3-(1,2-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50:  470nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2580(K252a | methyl (15R,16S,18S)-16-hydroxy-15-methyl-...)
Affinity DataIC50:  470nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2593((Arylindolyl)maleimide deriv. 15 | 3-(1-methyl-1H-...)
Affinity DataIC50:  480nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2608(3-(5-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50:  490nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50:  550nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2631(3-(1,4-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50:  590nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2610(3-(5-Methoxy-1-methyl-3-indolyl)-4-(1-methyl-3-ind...)
Affinity DataIC50:  600nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2652((Phenylindolyl)maleimide deriv. 74 | 3-(1-methyl-1...)
Affinity DataIC50:  670nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2597((Arylindolyl)maleimide deriv. 19 | 3-(1-methyl-1H-...)
Affinity DataIC50:  810nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2599((Arylindolyl)maleimide deriv. 21 | 3-(1-benzothiop...)
Affinity DataIC50:  900nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM2651((Phenylindolyl)maleimide deriv. 73 | 3-(2-chloroph...)
Affinity DataIC50:  900nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Products

LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  900nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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