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Found 38 with Last Name = 'wilman' and Initial = 'de'
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024544(3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataKi:  90nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataKi:  120nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024544(3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataKi:  200nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataKi:  480nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  600nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015985(3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015985(3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024544(3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024544(3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024550(3-Ethyl-1-heptyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024555(3-Nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024557(3-Pentyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dion...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024553(3-Ethyl-1-nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024547(3-Heptyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dion...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024546(3-Hexyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024548(3-Butyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024556(3-Propyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dion...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024559(3-Ethyl-1-hexyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024549(1-Decyl-3-ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015985(3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024543(3-Ethyl-1-pentyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024558(3-Ethyl-1-methyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024545(3-Ethyl-1-propyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024554(1-Butyl-3-ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015985(3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024553(3-Ethyl-1-nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  1.75E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024543(3-Ethyl-1-pentyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  2.09E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024550(3-Ethyl-1-heptyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024551(3-Methyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dion...)
Affinity DataIC50:  2.45E+5nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024549(1-Decyl-3-ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024552(1,3-Diethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-d...)
Affinity DataIC50:  3.85E+5nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed