Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at EP1 receptor assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Binding affinity to TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Activity at EP3 receptor by FLIPR methodMore data for this Ligand-Target Pair
Affinity DataKi: <6.31E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.129nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to rat EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity to human EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 50.1nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 50.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 63.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair