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Found 139 with Last Name = 'woo' and Initial = 'mh'
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataKi:  990nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092540(CHEMBL3586207)
Affinity DataKi:  1.17E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092531(CHEMBL3586199)
Affinity DataKi:  2.49E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50241345(Apigenin 7-O-β-D-glucuronide (9) | CHEMBL2542...)
Affinity DataKi:  2.60E+3nMAssay Description:The reaction mixtures contained in various different concentrations of p-NPP as a PTP1B substrate in the presence or absence of the active compound. ...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataKi:  2.80E+3nMAssay Description:The reaction mixtures contained in various different concentrations of p-NPP as a PTP1B substrate in the presence or absence of the active compound. ...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226157(PTP1B spring 7 (7))
Affinity DataKi:  3.00E+3nM ΔG°:  -32.8kJ/mole IC50:  4.80E+3nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060922(CHEMBL3394769)
Affinity DataKi:  3.00E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50093525(taiwaniaflavone)
Affinity DataKi:  4.50E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50259862(13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...)
Affinity DataKi:  4.60E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092529(CHEMBL3586197)
Affinity DataKi:  4.78E+3nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092533(CHEMBL3586201)
Affinity DataKi:  4.88E+3nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataKi:  6.40E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50323212(6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydro...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50129952(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataKi:  7.97E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060921(CHEMBL3394770)
Affinity DataKi:  8.90E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226153(Selaginellin U (2))
Affinity DataKi:  9.70E+3nM ΔG°:  -29.8kJ/mole IC50:  1.38E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060920(CHEMBL3394771)
Affinity DataKi:  1.03E+4nMAssay Description:Noncompetitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50093524(CHEMBL3585680)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50323213(CHEMBL1208973 | cupressuflavone)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226155(Selaginellin W (4))
Affinity DataKi:  1.11E+4nM ΔG°:  -29.4kJ/mole IC50:  1.46E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226154(Selaginellin V (3))
Affinity DataKi:  1.13E+4nM ΔG°:  -29.4kJ/mole IC50:  1.45E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226156(PTP1B spring 5 (5))
Affinity DataKi:  1.39E+4nM ΔG°:  -28.8kJ/mole IC50:  1.59E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060918(Selaginellin)
Affinity DataKi:  1.39E+4nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataKi:  1.45E+4nM ΔG°:  -28.7kJ/mole IC50:  1.32E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataKi:  1.45E+4nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060919(CHEMBL3394772)
Affinity DataKi:  1.51E+4nMAssay Description:Uncompetitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50303006(CHEMBL517247 | mulberrofuran D)
Affinity DataIC50:  90nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092540(CHEMBL3586207)
Affinity DataIC50:  220nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092529(CHEMBL3586197)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant BACE1 by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092537(CHEMBL3586204)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant BACE1 by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168024(CHEMBL3800462)
Affinity DataIC50:  390nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataIC50:  420nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168022(CHEMBL3797266)
Affinity DataIC50:  480nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168023(CHEMBL3800628)
Affinity DataIC50:  570nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50060923(CHEMBL3394773)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50303004(CHEMBL562810 | mulberrofuran W)
Affinity DataIC50:  700nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168019(CHEMBL3798170)
Affinity DataIC50:  710nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168021(CHEMBL3800241)
Affinity DataIC50:  760nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  770nMpH: 8.0 T: 2°CAssay Description:Briefly, 140 μL of sodium phosphate buffer (pH 8.0), 20 μL of each tested compound with different concentrations (4, 20, and 100 μM) a...More data for this Ligand-Target Pair
In DepthDetails
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168018(CHEMBL3798236)
Affinity DataIC50:  850nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092531(CHEMBL3586199)
Affinity DataIC50:  910nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50168020(CHEMBL3797932)
Affinity DataIC50:  920nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092530(CHEMBL3586198)
Affinity DataIC50:  980nMAssay Description:Inhibition of human recombinant BACE1 by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092527(CHEMBL3586196)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human recombinant BACE1 by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092533(CHEMBL3586201)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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