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Found 74 with Last Name = 'yang' and Initial = 'kw'
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174303(CHEMBL3809419)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of Bacillus cereus 569/H/9 metallo-beta-lactamase Bc2 expressed in Escherichia coli GI724 cells using nitrocefin as substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092976(CHEMBL3586478)
Affinity DataKi:  110nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092980(CHEMBL3586479)
Affinity DataKi:  170nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092982(CHEMBL3585360)
Affinity DataKi:  170nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092997(CHEMBL3586481)
Affinity DataKi:  190nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092979(CHEMBL3586477)
Affinity DataKi:  210nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092977(CHEMBL3586474)
Affinity DataKi:  280nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092842(CHEMBL3586476)
Affinity DataKi:  280nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092978(CHEMBL3586475)
Affinity DataKi:  410nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174181(CHEMBL3809806)
Affinity DataKi:  490nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174175(CHEMBL3808813)
Affinity DataKi:  630nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50093027(CHEMBL3586482)
Affinity DataKi:  870nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092981(CHEMBL3586480)
Affinity DataKi:  950nMAssay Description:Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Escherichia coli (strain K12))
Miami University

Curated by ChEMBL
LigandPNGBDBM50173997((1-aminoethyl)(2-carboxy-1-propenyl)phosphinic aci...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against aminopeptidase N (PepN) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Escherichia coli (strain K12))
Miami University

Curated by ChEMBL
LigandPNGBDBM50173996((1-aminoethyl)(2-carboxy-1-decyl)phosphinic acid |...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against aminopeptidase N (PepN) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089390(CHEMBL3577963)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174264(CHEMBL3808751)
Affinity DataKi:  1.28E+3nMAssay Description:Competitive inhibition of Bacillus cereus 569/H/9 metallo-beta-lactamase Bc2 expressed in Escherichia coli GI724 cells using nitrocefin as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089391(CHEMBL3577964)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089388(CHEMBL3577961)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089393(CHEMBL3577970)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089392(CHEMBL3577965)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089385(CHEMBL3577967)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089386(CHEMBL3577968)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089387(CHEMBL3577969)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089389(CHEMBL3577962)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Escherichia coli (strain K12))
Miami University

Curated by ChEMBL
LigandPNGBDBM50022572(3-[(1-Amino-ethyl)-hydroxy-phosphinoyl]-2-methyl-p...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against aminopeptidase N (PepN) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Escherichia coli (strain K12))
Miami University

Curated by ChEMBL
LigandPNGBDBM50173998(1-aminoethyl-N-1-carboxyethyl sulfonamidate | CHEM...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibitory activity against aminopeptidase N (PepN) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Escherichia coli (strain K12))
Miami University

Curated by ChEMBL
LigandPNGBDBM50173999(1-aminoethyl-O-1-carboxyethyl sulfonate | CHEMBL36...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibitory activity against aminopeptidase N (PepN) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089395(CHEMBL3577972)
Affinity DataKi: >2.50E+6nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089396(CHEMBL3577974)
Affinity DataKi: >5.00E+6nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Aeromonas veronii)
North-West University

Curated by ChEMBL
LigandPNGBDBM50089394(CHEMBL3577971)
Affinity DataKi: >5.00E+6nMAssay Description:Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092976(CHEMBL3586478)
Affinity DataIC50:  18nMAssay Description:Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092979(CHEMBL3586477)
Affinity DataIC50:  69nMAssay Description:Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174227(CHEMBL3810052)
Affinity DataIC50:  150nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174191(CHEMBL3809719)
Affinity DataIC50:  160nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174186(CHEMBL3808671)
Affinity DataIC50:  160nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174182(CHEMBL3809576)
Affinity DataIC50:  160nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174181(CHEMBL3809806)
Affinity DataIC50:  160nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174230(CHEMBL3809713)
Affinity DataIC50:  170nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174229(CHEMBL3808678)
Affinity DataIC50:  190nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174312(CHEMBL3809860)
Affinity DataIC50:  230nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092982(CHEMBL3585360)
Affinity DataIC50:  290nMAssay Description:Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174311(CHEMBL3808891)
Affinity DataIC50:  330nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174195(CHEMBL3809469)
Affinity DataIC50:  350nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174175(CHEMBL3808813)
Affinity DataIC50:  370nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174192(CHEMBL3809609)
Affinity DataIC50:  420nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50093027(CHEMBL3586482)
Affinity DataIC50:  450nMAssay Description:Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
North-West University

Curated by ChEMBL
LigandPNGBDBM50092842(CHEMBL3586476)
Affinity DataIC50:  450nMAssay Description:Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174309(CHEMBL3810122)
Affinity DataIC50:  450nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174306(CHEMBL3808797)
Affinity DataIC50:  480nMAssay Description:Inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells preincubated for 60 min followed by ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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