Affinity DataKi: 0.0500nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.130nM ΔG°: -56.4kJ/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitor potencies toward bovine carboxypeptidase A (Sigma-Aldrich Co) were determined in 96-well microplates format. Activity was monitored by meas...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitor potencies toward bovine carboxypeptidase A (Sigma-Aldrich Co) were determined in 96-well microplates format. Activity was monitored by meas...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of human somatic ACE in presence of bufferMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.3kJ/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair
Affinity DataKi: 1.25nM ΔG°: -50.8kJ/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity against matrix metalloprotease-9 (gelatinase-B).More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human somatic ACE in presence of bufferMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human somatic ACE in presence of 1:100 diluted SHR rat plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of Matrix metalloprotease-7 MatrilysinMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against matrix metalloprotease-11.More data for this Ligand-Target Pair