TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 2.97nM ΔG°: -49.5kJ/mole IC50: 6.99nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 6.66nM ΔG°: -47.5kJ/mole IC50: 15.6nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 7.17nM ΔG°: -47.3kJ/mole IC50: 16.9nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 9.34nM ΔG°: -46.6kJ/mole IC50: 21.9nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 11.1nM ΔG°: -46.2kJ/mole IC50: 26.1nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 38.7nM ΔG°: -43.0kJ/mole IC50: 91.0nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 49.2nM ΔG°: -42.4kJ/mole IC50: 116nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of The Chemistry Of Plant Substances
Curated by ChEMBL
Institute Of The Chemistry Of Plant Substances
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Competitive inhibition of HMG-CoA reductase by Dixon plot analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of The Chemistry Of Plant Substances
Curated by ChEMBL
Institute Of The Chemistry Of Plant Substances
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Competitive inhibition of HMG-CoA reductase by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of HIV1 recombinant proteaseMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human BACE1 proteolytic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GSK3beta at 5 uMMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of GSK3beta at 5 uMMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site by sAPP_NF cell based assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair