TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dual luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual lucifer...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair