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Found 188 with Last Name = 'zherebina' and Initial = 'y'
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207351(CHEMBL3965256)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207359(CHEMBL3892377)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207353(CHEMBL3949755)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207349(CHEMBL3958414)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207350(CHEMBL3956954)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207355(CHEMBL3987106)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207353(CHEMBL3949755)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207365(CHEMBL3899046)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Affinity DataIC50:  1.5nMAssay Description:Reversible/competitive inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infec...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207356(CHEMBL3969464)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207352(CHEMBL3908093)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  2nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207354(CHEMBL3961368)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207362(CHEMBL3977870)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM357385(US10214519, Example 111)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50070322(CHEMBL3408248 | US9718800, 3.06b)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207361(CHEMBL3889951)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207350(CHEMBL3956954)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207355(CHEMBL3987106)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207364(CHEMBL3936048)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207348(CHEMBL3912281)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207349(CHEMBL3958414)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50541951(CHEMBL4634912)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207356(CHEMBL3969464)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368724(US10227350, Compound 139 | US10227350, Compound 14...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368743(US10227350, Compound 158)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207365(CHEMBL3899046)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368688(US10227350, Compound 103 | US10227350, Compound 10...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368626(US10227350, Compound 141 | US10227350, Compound 14...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368724(US10227350, Compound 139 | US10227350, Compound 14...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368724(US10227350, Compound 139 | US10227350, Compound 14...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207352(CHEMBL3908093)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368626(US10227350, Compound 141 | US10227350, Compound 14...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207354(CHEMBL3961368)
Affinity DataIC50:  10nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368626(US10227350, Compound 141 | US10227350, Compound 14...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368688(US10227350, Compound 103 | US10227350, Compound 10...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368688(US10227350, Compound 103 | US10227350, Compound 10...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207348(CHEMBL3912281)
Affinity DataIC50:  11nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM368687(US10227350, Compound 102)
Affinity DataIC50:  11nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM357385(US10214519, Example 111)
Affinity DataIC50:  12nMAssay Description:Inhibition of human p110delta catalytic subunit/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM368741(US10227350, Compound 156)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207362(CHEMBL3977870)
Affinity DataIC50:  14nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207361(CHEMBL3889951)
Affinity DataIC50:  17nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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