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Found 55 with Last Name = 'zhu' and Initial = 'js'
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512539(CHEMBL4466170)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512543(CHEMBL4546564)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512535(CHEMBL4435424)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512536(CHEMBL4446784)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512537(CHEMBL4474736)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Homo sapiens)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512537(CHEMBL4474736)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512531(CHEMBL4577192)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512530(CHEMBL4546431)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512529(CHEMBL4436619)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512528(CHEMBL4590521)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512527(CHEMBL4529094)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512532(CHEMBL4444063)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512533(CHEMBL4575750)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512534(CHEMBL4578218)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512538(CHEMBL4576357)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512540(CHEMBL4444793)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512541(CHEMBL4571849)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPendrin(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50512542(CHEMBL4445120)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237270(CHEMBL4084118)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237271(CHEMBL4102104)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237272(CHEMBL4068990)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237273(CHEMBL4082320)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237274(CHEMBL4060418)
Affinity DataEC50:  65nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237275(CHEMBL4098817)
Affinity DataEC50:  55nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237276(CHEMBL4091072)
Affinity DataEC50:  4.30E+3nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237277(CHEMBL4086433)
Affinity DataEC50:  200nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237256(CHEMBL4068723)
Affinity DataEC50:  9nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237278(CHEMBL4093693)
Affinity DataEC50:  330nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237279(CHEMBL4084994)
Affinity DataEC50:  550nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237280(CHEMBL4061323)
Affinity DataEC50:  760nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237281(CHEMBL4064125)
Affinity DataEC50:  63nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237282(CHEMBL4096257)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237283(CHEMBL4071817)
Affinity DataEC50:  177nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237284(CHEMBL4083281)
Affinity DataEC50:  20nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237285(CHEMBL4092001)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237252(CHEMBL4071923)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237269(CHEMBL4072713)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237268(CHEMBL4099611)
Affinity DataEC50:  110nMAssay Description:In vitro inhibition of geranylgeranyl-protein transferase type-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237267(CHEMBL4083185)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237266(CHEMBL4097026)
Affinity DataEC50:  18nMAssay Description:In vitro inhibition of farnesyl-protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237265(CHEMBL4069832)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237264(CHEMBL4063348)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237263(CHEMBL4101412)
Affinity DataEC50:  690nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237262(CHEMBL4074724)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237261(CHEMBL4066115)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237260(CHEMBL4085942)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237259(CHEMBL4103866)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237258(CHEMBL4089825)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237257(CHEMBL4064970)
Affinity DataEC50:  9.90E+3nMAssay Description:Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50237256(CHEMBL4068723)
Affinity DataEC50:  21nMAssay Description:Activation of human CFTR expressed in forskolin-stimulated basolateral membrane permeabilized FRT cells assessed as increase in short-circuit current...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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