TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 138nMAssay Description:Mixed type inhibition of bovine xanthine oxidase assessed as inhibitory constant using xanthine as substrate preincubated for 25 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Central South University
Curated by ChEMBL
Central South University
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of aldose reductase by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 299nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 25 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 375nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Central South University
Curated by ChEMBL
Central South University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of aldose reductase by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 25 mins followed by s...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 445nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 445nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 453nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 472nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Xiangtan University
Curated by ChEMBL
Xiangtan University
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of aldose reductase from calf lense by AR assayMore data for this Ligand-Target Pair