Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 34 hits in this display
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Ki: 2.85E+3nMAssay Description:Competitive inhibition of IDH1-R132H mutant (unknown origin) using a-ketoglutarate and NADPH as substrate by steady state kinetic analysisMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Ki: 3.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Sialidase(Clostridium perfringens)Graduate School Of Gyeongsang National University
Curated by ChEMBL
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 2.81E+3nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 5.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 5.70E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured for 15 mins by spectrophotometryMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 7.70E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Sialidase(Clostridium perfringens)Graduate School Of Gyeongsang National University
Curated by ChEMBL
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 1.41E+4nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Aromatase(Homo sapiens (Human))University Of Illinois At Chicago
Curated by ChEMBL
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
IC50: 2.47E+4nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Kd: 1.57E+5nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) assessed as dissociation constant by DSF methodMore data for this Ligand-Target Pair
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
BDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)