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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  57nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  3.12E+3nMAssay Description:Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin A chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  36nMAssay Description:Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed