Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of 20S immunoproteasome beta-5i subunit in human PBMC using Ac-ANW-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human A549 cells using Suc-LLVY-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human 20S proteasome beta5 subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-7(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 20S proteasome beta2 subunit using Ac-RLR-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta-2i subunit using Ac-RLR-AMC as substrate preincubated for 2 hrs followed by substrate addition and meas...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta-1i subunit using (Ac-PAL)2R110 as substrate preincubated for 2 hrs followed by substrate addition and m...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails PubMed