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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Berlex Biosciences
Ligand
BDBM17052
(BX-912 | N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)et...)
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Affinity Data
IC50: 12nM
pH: 7.2 T: 2°C
Assay Description:
The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PubMed
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM17052
(BX-912 | N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)et...)
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Affinity Data
IC50: 338nM
Assay Description:
Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM17052
(BX-912 | N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)et...)
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Affinity Data
IC50: 2.33E+3nM
Assay Description:
Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM17052
(BX-912 | N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)et...)
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Copy InChI
Affinity Data
IC50: 3.33E+3nM
Assay Description:
Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI