Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM210747(US9290454, 1.2)Copy SMILESCopy InChI

Affinity DataKi:  49nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM210747(US9290454, 1.2)Copy SMILESCopy InChI

Affinity DataKi:  49.0nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI