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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Coagulation factor XI
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM241588
(US9409908, 220 | US9951071, Example 220)
Copy SMILES
Affinity Data
Ki: 21.7nM
Assay Description:
Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Coagulation factor IX
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM241588
(US9409908, 220 | US9951071, Example 220)
Copy SMILES
Affinity Data
Ki: 21.7nM
pH: 7.4
Assay Description:
Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Plasma kallikrein
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM241588
(US9409908, 220 | US9951071, Example 220)
Copy SMILES
Affinity Data
Ki: 50.2nM ΔG°: -43.3kJ/mole
T: 2°C
Assay Description:
Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Plasma kallikrein
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM241588
(US9409908, 220 | US9951071, Example 220)
Copy SMILES
Affinity Data
Ki: 50.2nM
Assay Description:
Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI