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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50012662
(CHEMBL3261075)
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Affinity Data
IC50: 1.30nM
Assay Description:
Inhibition of BACE1 in human SKNBE2 cells expressing wild type amyloid precursor protein (APP695) assessed as amyloid beta42 level incubated for 18 h...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50012662
(CHEMBL3261075)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.20nM
Assay Description:
Inhibition of BACE1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50012662
(CHEMBL3261075)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
Assay Description:
Inhibition of recombinant BACE1 (unknown origin) using APP swedish mutant as substrate containing (7-methoxycoumarin-4-yl) acetic acid/2,4-Dinitrophe...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Beta-secretase 2
(Homo sapiens (Human))
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50012662
(CHEMBL3261075)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of BACE2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 1
(Homo sapiens)
Janssen Research & Development
Curated by
ChEMBL
Ligand
BDBM50012662
(CHEMBL3261075)
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Copy InChI
Affinity Data
IC50: 490nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI