Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 11 hits in this display
IC50: 2.80E+3nMAssay Description:Inhibition of PARP3 (unknown origin) using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assayMore data for this Ligand-Target Pair
IC50: >3.00E+3nMAssay Description:Inhibition of TNSK1/2-activated Wnt pathway in human DLD-1 TOPFlash/EF1a Renilla reporter cells after 24 hrs by Steady-Glo Luciferase assayMore data for this Ligand-Target Pair
EC50: 30nMAssay Description:Inhibition of PARP in human HCC1806 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
EC50: 30nMAssay Description:Inhibition of PARP in human MDA-MB-157 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
EC50: 123nMAssay Description:Inhibition of PARP in human MCF7 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
EC50: 53nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair