Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProgesterone receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL

LigandBDBM50364468(CHEMBL1950698)Copy SMILESCopy InChI

Affinity DataIC50:  41nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlucocorticoid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL

LigandBDBM50364468(CHEMBL1950698)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI