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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
A*Star
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 38nM
Assay Description:
Inhibition of Mnk2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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PubMed
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Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
A*Star
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 43nM
Assay Description:
Inhibition of human lung HIS-tagged Mnk1 transfected in Sf9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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PubMed
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Target
Protein kinase C-like 1
(Candida albicans)
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 44nM
Assay Description:
Inhibition of Candida albicans Pkc1 expressed in insect Sf9 cells by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
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Article
PubMed
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Target
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 220nM
Assay Description:
Inhibition of recombinant human CDK9/CyclinT using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Protein kinase C beta type
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 300nM
Assay Description:
Inhibition of human PKCbeta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Protein kinase C beta type
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 350nM
Assay Description:
Inhibition of human PKCbeta by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 770nM
Assay Description:
Inhibition of recombinant human CDK2/Cyclin A using ATP and Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of human PKCalpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 1.02E+3nM
Assay Description:
Inhibition of human PKCalpha by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of human Aurora-B using full-length histone H3 as substrate after 10 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 5.60E+3nM
Assay Description:
Inhibition of human CDK5/p25
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Protein kinase C gamma type
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 5.80E+3nM
Assay Description:
Inhibition of human PKCgamma by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: 8.10E+3nM
Assay Description:
Inhibition of recombinant human PIM1 using CREBtide as substrate after 60 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Glycogen synthase kinase-3 beta
(Sus scrofa)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of pig GSK3beta using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Dual specificity protein kinase CLK1
(Mus musculus)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of mouse CLK1 using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
[Tau protein] kinase
(Sus scrofa)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
Copy SMILES
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of pig GSK3alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 60 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Casein kinase I isoform epsilon
(Sus scrofa)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of pig CK1epsilon using Ulight-ARTKQTARKSTGGKAPRKQLAGCG as substrate after 60 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of rat Dyrk1a using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Casein kinase 1, delta tv1
(Sus scrofa)
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of pig CK1delta
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase haspin
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50256734
((-)-Cercosporamide | CHEMBL475816)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human haspin using full-length histone H3 as substrate after 10 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI