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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
61
hits in this display
Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 2nM
Assay Description:
Inhibition of recombinant PLK3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
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Target
Serine/threonine-protein kinase PLK2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 2nM
Assay Description:
Inhibition of recombinant PLK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 5nM
Assay Description:
Inhibition of recombinant GST-tagged PLK1 using biotin-ahx-AKMETTFYDDALNASFLPSEKKK-amide as substrate after 30 mins by scintillation counting analysi...
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Target
Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 7nM
Assay Description:
Inhibition of recombinant PLK4 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target Info
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 7.90nM
Assay Description:
Inhibition of recombinant PKCdelta after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 14nM
Assay Description:
Inhibition of recombinant FLT1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 21nM
Assay Description:
Inhibition of recombinant GSK3A after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 71nM
Assay Description:
Inhibition of recombinant PDK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 88nM
Assay Description:
Inhibition of recombinant CHK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 98nM
Assay Description:
Inhibition of recombinant KDR after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target Info
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 102nM
Assay Description:
Inhibition of recombinant GSK3B after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 167nM
Assay Description:
Inhibition of recombinant CHK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Polycystin-2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 175nM
Assay Description:
Inhibition of recombinant PKD2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
LIM domain kinase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 194nM
Assay Description:
Inhibition of recombinant LIMK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
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Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 220nM
Assay Description:
Inhibition of recombinant ROCK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 260nM
Assay Description:
Inhibition of recombinant SGK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 262nM
Assay Description:
Inhibition of recombinant JNK2A2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 328nM
Assay Description:
Inhibition of recombinant FYN after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
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Target
5'-AMP-activated protein kinase subunit beta-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 333nM
Assay Description:
Inhibition of recombinant AMPK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 416nM
Assay Description:
Inhibition of recombinant CDK5 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 430nM
Assay Description:
Inhibition of recombinant ROCK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 494nM
Assay Description:
Inhibition of recombinant FLT3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 630nM
Assay Description:
Inhibition of recombinant RSK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >700nM
Assay Description:
Inhibition of recombinant ABL after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 920nM
Assay Description:
Inhibition of recombinant JAK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.40E+3nM
Assay Description:
Inhibition of recombinant PIM2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.40E+3nM
Assay Description:
Inhibition of recombinant BLK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.40E+3nM
Assay Description:
Inhibition of recombinant ERBB2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 1.40E+3nM
Assay Description:
Inhibition of recombinant FGFR3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
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Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.50E+3nM
Assay Description:
Inhibition of recombinant ITK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 1.60E+3nM
Assay Description:
Inhibition of recombinant c-MET after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: 1.60E+3nM
Assay Description:
Inhibition of recombinant PIM1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.60E+3nM
Assay Description:
Inhibition of recombinant LYN after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.70E+3nM
Assay Description:
Inhibition of recombinant JAK3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Affinity Data
Ki: >1.80E+3nM
Assay Description:
Inhibition of recombinant EGFR after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >1.80E+3nM
Assay Description:
Inhibition of recombinant IGF1R after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >1.90E+3nM
Assay Description:
Inhibition of recombinant TYK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >1.90E+3nM
Assay Description:
Inhibition of recombinant SRC after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 2.10E+3nM
Assay Description:
Inhibition of recombinant CSF1R after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >2.40E+3nM
Assay Description:
Inhibition of recombinant TRKA after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >2.80E+3nM
Assay Description:
Inhibition of recombinant EPHA2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 2.90E+3nM
Assay Description:
Inhibition of recombinant MST2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >3.00E+3nM
Assay Description:
Inhibition of recombinant JNK1A1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 3.61E+3nM
Assay Description:
Inhibition of recombinant EMK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >3.70E+3nM
Assay Description:
Inhibition of recombinant ERBB4 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Cell division control protein 42 homolog
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >4.40E+3nM
Assay Description:
Inhibition of recombinant CDC42 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >4.50E+3nM
Assay Description:
Inhibition of recombinant TRKB after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 4.83E+3nM
Assay Description:
Inhibition of recombinant CTAK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Mitogen-activated protein kinase 13
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 5.90E+3nM
Assay Description:
Inhibition of recombinant P38delta after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >6.80E+3nM
Assay Description:
Inhibition of recombinant DYRK1A after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: 7.20E+3nM
Assay Description:
Inhibition of recombinant ERK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >7.80E+3nM
Assay Description:
Inhibition of recombinant CK1delta after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >8.00E+3nM
Assay Description:
Inhibition of recombinant AKT2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >8.00E+3nM
Assay Description:
Inhibition of recombinant AKT1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >8.50E+3nM
Assay Description:
Inhibition of recombinant CAMK4 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >9.00E+3nM
Assay Description:
Inhibition of recombinant AKT3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
MAP kinase-activated protein kinase 3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >9.20E+3nM
Assay Description:
Inhibition of recombinant MK3 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >9.20E+3nM
Assay Description:
Inhibition of recombinant NEK2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase PAK 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >9.70E+3nM
Assay Description:
Inhibition of recombinant PAK1 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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Ki: >9.90E+3nM
Assay Description:
Inhibition of recombinant IRAK4 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50402020
(CHEMBL2205426)
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EC50: 1.05E+3nM
Assay Description:
Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assay
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