Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 27 hits in this display
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 16nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Uncharacterized protein(Cryptosporidium parvum)University of Washington Through Its Center For Commercialization
US Patent
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 16nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 59nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 59nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 375nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 500nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 1.90E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 6.00E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
IC50: 6.00E+3nMAssay Description:Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...More data for this Ligand-Target Pair
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
BDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)