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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50393560
(CHEMBL2158300 | US8697716, 48)
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Affinity Data
IC50: 0.620nM
Assay Description:
Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarization
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM50393560
(CHEMBL2158300 | US8697716, 48)
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Affinity Data
IC50: 5nM
Assay Description:
The compounds of the present invention are also specific inhibitors of c-Kit. Selection of preferred compounds of Formula I for use as c-Kit inhibito...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Mus musculus (Mouse))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50393560
(CHEMBL2158300 | US8697716, 48)
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Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of FMS-mediated proliferation in CSF1-stimulated bone marrow-derived mouse macrophages assessed as inhibition of incorporation of bromodeo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI