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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Coagulation factor X
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: 15nM
Assay Description:
Binding affinity to factor 10a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: >2.50E+4nM
Assay Description:
Inhibition of thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor IX
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of factor 9a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor XI
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Copy InChI
Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of factor 11a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor VII/Tissue factor
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of tissue factor/factor 7a
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vitamin K-dependent protein C
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of activated protein C
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
Ki: >3.30E+4nM
Assay Description:
Inhibition of plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50324744
((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
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Affinity Data
IC50: 1.20E+4nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI