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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Affinity Data
IC50: 126nM
Assay Description:
Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assay
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UniProtKB/SwissProt
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...
More data for this Ligand-Target Pair
Target Info
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Target
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
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Target Info
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Target
Protein mono-ADP-ribosyltransferase PARP11
(Homo sapiens)
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
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Target
Protein mono-ADP-ribosyltransferase PARP14
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Affinity Data
IC50: <5.01E+3nM
Assay Description:
Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...
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Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP2 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP1 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
antibodypedia
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CHEMBL
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Article
PubMed
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Target
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
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Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP10 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
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Target
Protein mono-ADP-ribosyltransferase PARP16
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238425
(CHEMBL4064332)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI