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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM134608
(US8846698, 71)
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Affinity Data
Ki: 7.10E+3nM
Assay Description:
Inhibition of dofetilide binding to human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM134608
(US8846698, 71)
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Affinity Data
IC50: 42nM
Assay Description:
Inhibition of human TrkB expressed in human U2OS cells pre-incubated 30 mins before neurotrophin addition and measured after 2 hrs by luminescence ba...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM134608
(US8846698, 71)
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Affinity Data
IC50: 62nM
Assay Description:
Inhibition of human TrkA expressed in human U2OS cells pre-incubated 30 mins before neurotrophin addition and measured after 2 hrs by luminescence ba...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM134608
(US8846698, 71)
Copy SMILES
Copy InChI
Affinity Data
IC50: 135nM
Assay Description:
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
US Patent
PDB
3D Structure (crystal)
Copy BDB DOI