Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  12nMAssay Description:Inhibition of factor 11a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  49nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetProthrombin(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  218nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor XII(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  241nMAssay Description:Inhibition of factor 12a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor VII(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  461nMAssay Description:Inhibition of factor 7a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTrypsin(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  547nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor IX(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50543719(CHEMBL4646710)Copy SMILESCopy InChI

Affinity DataIC50:  7.83E+3nMAssay Description:Inhibition of factor 9a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI